Cadron Creek is a whitewater canoeing stream that begins south of Heber Springs in Cleburne County. The creek flows mostly west for fifty-nine miles before joining the Arkansas River near Cadron Settlement Park in Faulkner County.
The headwaters of Cadron Creek is located near the north shoulder of Arkansas Highway 16 as it snakes southeast out of Heber Springs. The elevation of the creek at this point is about 800 feet above sea level. The mouth of Pierce Branch is found on the creek about four thousand feet northeast of Pearson. The mouth of Taylor Creek is less than a thousand feet northwest of Pearson. Cadron Creek then runs west-south-west along the north face of Bettis Mountain, with Jackson Creek and several others running into it from the north. The creek darts south on the west side of Bettis Mountain, and is joined by Beaver Creek. The creek then continues west-south-west, bisecting hilly country south of White Oak Mountain and Batesville Mountain. Below Batesville Mountain the creek is joined by the Kennimer Branch, King Branch, Stillhouse Branch, and Wolf Branch. Above Pinnacle Point Gap the creek turns straight south before turning west again and running under U.S. Highway 65 half way between Damascus and Greenbrier. The creek winds its way west through a canyon at this point, and has an elevation of about 400 feet above sea level.
Cove Creek joins the Cadron just southwest of Pin Oak Break. The creek turns south, and even moves a little to the south-southeast before reaching the mouth of Greenbrier Creek and East Fork Cadron Creek. The creek flows mostly south from here until it reaches U.S. Highway 64 near Gleason. The creek then darts west, north, and southwest before reaching the Arkansas River.