Blackwell is an unincorporated town near the western border of Conway County, Arkansas. The community is on U.S. Highway 64 and is served by Interstate 40 interchange number 101. Nearby businesses include the Blackwell Truck Stop, D & R Implement, The Trailer Store, and Fat Daddy's Bar B Que. St. Matthews Baptist Church is in Blackwell.
A U.S. Post Office was established here on September 13, 1897.